Introduction
A walking blood bank is hardly a new concept. In fact, they have existed since World War I and were used routinely until after the Vietnam War. It was not until the 1960s that blood donations were broken down into red blood cells, plasma, and platelets. With the advantages of longer storage time, improved blood safety, and ability to more effectively use each donation, blood component therapy became the standard and the use of whole blood nearly disappeared.
Since the conflicts in Iraq and Afghanistan, however, whole blood has come back into fashion, particularly in the military. Whole blood has been shown to be at least as effective as transfusing blood products in a 1:1:1 ratio of packed red blood cells, thawed fresh frozen plasma, and five pack of platelets and has the advantage of being available in every human. Setting up a walking blood bank is a practical and efficient way to obtain whole blood quickly in circumstances where the use of stored blood is not feasible.
Preparation
In order to start a walking blood bank, several questions need to be answered. First, is there a need? Weighing the likelihood of massive hemorrhage or a mass casualty event versus the availability of stored whole blood can give a good indication as to whether the effort to build a blood bank will be worthwhile. Next, what protocol fits that need? The military has several and a few exist on the civilian side as well, but each will need adjustment based on specific circumstances. One of the biggest debates is whether to use a low titer O positive approach or aim for type-specific blood. O type blood is the universal donor, but all O blood contains some A and B antibodies; low titer donors have low amounts of these antibodies and are less likely to cause a transfusion reaction. It is not always possible to test for low titer donors, however, so some advocate for prioritizing type-specific blood if available, although this is falling out of favor.